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guilherme_deoliveira
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In cases where Trusted RFCs are not working, the easiest solution is to delete the trusted relationship and re-build it. However, before doing that, please make sure that you have SAP Note 1491645 implemented in both systems of the trusting relationship.

In summary:

  1. Delete the affected destinations in SM59 and SMT1.
  2. Re-create the trusted relationship:

NOTE: Make sure that user being used to re-create the trusted relationship has enough authorization. Even if user has SAP_ALL, notice that S_RFC and S_RFCACL authorizations are also required.

I hope this helps.

Best Regards,

Guilherme de Oliveira.