As far as i know SAP does not provide a tool for mass upload of notes and i can see why, basically each note containes changes from programs to tables,etc... and you wouldn't like to do this without confirmation that the note was implemented successfully before proceeding with the next one. also as mentioned earlier some notes have dependencies so you'll need to make sure that the notes are implemented in the right order.
As mentioned by Pinkle most of the notes are already included in the latest SP's so you're better updating the system stack or the necesary SP's to reduce the ammount of notes to implement
That mass note download / application could be interesting when you are using RSECNOTE (ST13).
You usually get a bunch of notes recommended by that tools ... it can ask you to apply almost 30 notes...
and it is a pain to apply them one by one.
I know that the best way should be to run that tools on a regular basis ...